Cell & Gene Therapy Insights – Trince spotlight
January 31, 2023
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A gentler cell transfection method
Photoporation is a gentle method to deliver payloads into cells based on the interaction between pulsed laser light and photothermal nanosensitizers.
View our
product video
A gentler cell transfection method
Photoporation is a gentle method to deliver payloads into cells based on the interaction between pulsed laser light and photothermal nanosensitizers.
View our
product video
Photoporation is based on the interaction between pulsed laser light and photothermal nanosensitizers.
After incubation of cells with nanosensitizers, localized light-induced thermal and mechanical forces form transient pores in the cellular membrane. External payloads can enter the cellular cytosol through these pores with minimal impact on cell viability and functionality.
Our proprietary nanosensitizers can be used as a suspension for R&D applications or can be embedded in a nanofiber structure for clinical applications.
Minimal damage to the cell membrane means faster cell recovery and better preservation of functionality
Thanks to being gentle to cells, a high yield of transfected cells is achieved
Deliver a large variety of payloads (gene editing complexes, nucleic acids, contrast agents, proteins,…) to a broad range of cell types (immune cells, stem cells, neurons…)
No need for exchanging cell media – use in any transparent cell recipient (96-well plates, T-flasks, etc.)
Discover how it works
Photoporation is based on the interaction between pulsed laser light and photothermal nanosensitizers.
After incubation of cells with nanosensitizers, localized light-induced thermal and mechanical forces form transient pores in the cellular membrane. External payloads can enter the cellular cytosol through these pores with minimal impact on cell viability and functionality.
Our proprietary nanosensitizers can be used as a suspension for R&D applications or can be embedded in a nanofiber structure for clinical applications.
Minimal damage to the cell membrane means faster cell recovery and better preservation of functionality
Thanks to being gentle to cells, a high yield of transfected cells is achieved
Deliver a large variety of payloads (gene editing complexes, nucleic acids, contrast agents, proteins,…) to a broad range of cell types (immune cells, stem cells, neurons…)
No need for exchanging cell media – use in any transparent cell recipient (96-well plates, T-flasks, etc.)
Discover how it works
Transfected cells recover
quickly and grow without delay
Transfect cells directly in typical cell culture recipients; transfected cells recover quickly
Spacially resolved transfections, down to single cell precision
Transfected cells recover
quickly and grow without delay
Transfect cells directly in typical cell culture recipients; transfected cells recover quickly
Spacially resolved transfections, down to single cell precision
Interested in using our
platform for your clinical
research or R&D applications?
Join our early access program
Learn more about Trince
Stay up to date on all
our latest research and news
Read our latest news
Paris, May 31-June 3, 2023
Carlsbad, October 10-12, 2023
Interested in using our platform for your clinical research or R&D applications?
Join our early access program
Learn more about Trince
Read our latest news
Paris, May 31-June 3, 2023
Carlsbad, October 10-12, 2023
Stay up to date on all
our latest research and news
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